发明授权
US07339035B2 Antibody recognizing GM1 ganglioside-bound amyloid β-protein and DNA encoding the antibody
有权
识别GM1神经节苷脂结合淀粉样β蛋白的抗体和编码抗体的DNA
- 专利标题： Antibody recognizing GM1 ganglioside-bound amyloid β-protein and DNA encoding the antibody
- 专利标题（中）： 识别GM1神经节苷脂结合淀粉样β蛋白的抗体和编码抗体的DNA
-
申请号： US10768193申请日： 2004-02-02
-
公开(公告)号： US07339035B2公开(公告)日： 2008-03-04
- 发明人: Katsuhiko Yanagisawa , Masao Shibata
- 申请人： Katsuhiko Yanagisawa , Masao Shibata
- 申请人地址： JP Nagoya-shi JP Obu-shi JP Obu-shi
- 专利权人： Medical & Biological Laboratories Co., Ltd.,Japan as Represented by the Director of Chubu National Hospital,Katsuhiko Yanagisawa
- 当前专利权人： Medical & Biological Laboratories Co., Ltd.,Japan as Represented by the Director of Chubu National Hospital,Katsuhiko Yanagisawa
- 当前专利权人地址： JP Nagoya-shi JP Obu-shi JP Obu-shi
- 代理机构： Edwards Angell Palmer & Dodge LLP
- 优先权： JP2001-235700 20010803
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; C07K16/00
摘要：
It is intended to provide an antibody efficacious in diagnosing, preventing or treating Alzheimer's disease, DNA encoding the antibody, a method of screening a drug and drugs. The amino acid sequence and the gene sequence of the variable region of an antibody, which specifically recognizes a GM1 ganglioside-bound amyloid β-protein occurring in the early stage of β-amyloid fibril formation, are determined. Based on the data of the amino acid sequence and the gene sequence thus obtained, an antibody is designed.
公开/授权文献
信息查询
