发明授权
US07348346B2 Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV)
失效
药物组合物作为二肽基肽酶-IV(DPP-IV)的抑制剂
- 专利标题: Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV)
- 专利标题(中): 药物组合物作为二肽基肽酶-IV(DPP-IV)的抑制剂
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申请号: US11075319申请日: 2005-03-08
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公开(公告)号: US07348346B2公开(公告)日: 2008-03-25
- 发明人: Irini Akritopoulou-Zanze , Daria Darczak , Jürgen Dinges , Stevan W. Djuric , Ethan D. Hoff , Hana A. Kopecka , Jyoti R. Patel , Zhonghua Pei , Qi Shuai , Kathy Sarris , Hing L. Sham , Paul E. Wiedeman
- 申请人: Irini Akritopoulou-Zanze , Daria Darczak , Jürgen Dinges , Stevan W. Djuric , Ethan D. Hoff , Hana A. Kopecka , Jyoti R. Patel , Zhonghua Pei , Qi Shuai , Kathy Sarris , Hing L. Sham , Paul E. Wiedeman
- 申请人地址: US IL Abbott Park
- 专利权人: Abbott Laboratories
- 当前专利权人: Abbott Laboratories
- 当前专利权人地址: US IL Abbott Park
- 代理商 Andrew M. Parial; Johanna M. Corbin
- 主分类号: A61K31/426
- IPC分类号: A61K31/426 ; A61K31/4025 ; C07D277/04
摘要:
The present invention relates to compounds of formula (I), which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, syndrome X, hyperinsulinemia, obesity, atherosclerosis, and various immunomodulatory diseases.
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