发明授权
- 专利标题: Antibodies to G protein-coupled receptor
- 专利标题(中): G蛋白偶联受体的抗体
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申请号: US10991028申请日: 2004-11-16
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公开(公告)号: US07351583B2公开(公告)日: 2008-04-01
- 发明人: Arthur B. Raitano , Daniel E. H. Afar , Aya Jakobovits , Mary Faris , Rene S. Hubert , Steven Chappell Mitchell , Douglas Saffran
- 申请人: Arthur B. Raitano , Daniel E. H. Afar , Aya Jakobovits , Mary Faris , Rene S. Hubert , Steven Chappell Mitchell , Douglas Saffran
- 申请人地址: US CA Santa Monica
- 专利权人: Agensys, Inc.
- 当前专利权人: Agensys, Inc.
- 当前专利权人地址: US CA Santa Monica
- 代理机构: Morrison & Foerster LLP
- 主分类号: C12N15/85
- IPC分类号: C12N15/85
摘要:
A novel gene (designated PHOR-1) that is highly over-expressed in prostate and other cancers and its encoded protein are described. PHOR-1 is a G protein-coupled receptor with homology to receptors involved in olfaction. PHOR-1 in normal human tissues is restricted to prostate, and this gene is highly over-expressed in prostate cancer as well as in cancers of the kidney, uterus, cervix, stomach and rectum. Consequently, PHOR-1 provides a diagnostic and/or therapeutic target for prostate cancer.
公开/授权文献
- US20070275437A1 Antibodies to G protein-coupled receptor 公开/授权日:2007-11-29
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