Invention Grant
- Patent Title: Azole derivatives and methods for making the same
- Patent Title (中): 唑衍生物和制备方法
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Application No.: US11289348Application Date: 2005-11-29
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Publication No.: US07351731B2Publication Date: 2008-04-01
- Inventor: Keykavous Parang , Soroush Sardari , Nguyen Hai Nam
- Applicant: Keykavous Parang , Soroush Sardari , Nguyen Hai Nam
- Applicant Address: US RI Providence
- Assignee: Board of Governors for Higher Education, State of Rhode Island and Providence Plantations
- Current Assignee: Board of Governors for Higher Education, State of Rhode Island and Providence Plantations
- Current Assignee Address: US RI Providence
- Agency: Gauthier & Connors, LLP
- Main IPC: A61K31/4196
- IPC: A61K31/4196 ; C07D249/08

Abstract:
The present invention is broadly directed to azole derivatives that exhibit antifungal activity and methods for making the same. In one aspect, the invention includes carboxylic acid and phosphate ester derivatives of fluconazole that exhibit antifungal activity. In addition, the invention comprises methods for synthesizing the derivatives and pharmaceutical compositions containing the derivatives.
Public/Granted literature
- US20060142361A1 Azole derivatives and methods for making the same Public/Granted day:2006-06-29
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