Invention Grant
US07368257B2 Modulators of lymphocyte activation, Mkk3b compositions and methods of use
有权
淋巴细胞活化调节剂，Mkk3b组成和使用方法
- Patent Title: Modulators of lymphocyte activation, Mkk3b compositions and methods of use
- Patent Title (中): 淋巴细胞活化调节剂，Mkk3b组成和使用方法
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Application No.: US10495901Application Date: 2002-11-18
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Publication No.: US07368257B2Publication Date: 2008-05-06
- Inventor: Alan C. Fu , Jun Wu , X. Charlene Liao , Helena Mancebo
- Applicant: Alan C. Fu , Jun Wu , X. Charlene Liao , Helena Mancebo
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Incorporated
- Current Assignee: Rigel Pharmaceuticals, Incorporated
- Current Assignee Address: US CA South San Francisco
- Agency: Klarquist Sparkman LLP
- International Application: PCT/US02/36881 WO 20021118
- International Announcement: WO03/044529 WO 20030530
- Main IPC: C12Q1/48
- IPC: C12Q1/48 ; C12Q1/02 ; C12P21/06
Abstract:
The present invention provides compositions and methods for modulating lymphocyte activation. Nucleic acids encoding proteins and proteins so encoded which are capable of modulating lymphocyte activation are provided. Compositions and methods for the treatment of disorders related to lymphocyte dysfunction or dysregulation are also provided. Prophylactics and methods for the prevention of such disorders are also provided. Also provided are compositions and methods for diagnostic and prognostic determination of such disorders. Further provided are assays for the identification of bioactive agents capable of modulating lymphocyte activation.
Public/Granted literature
- US20050170434A1 Modulators of lymphocyte activation, mkk3b compositions and methods of use Public/Granted day:2005-08-04
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