发明授权
US07368257B2 Modulators of lymphocyte activation, Mkk3b compositions and methods of use
有权
淋巴细胞活化调节剂，Mkk3b组成和使用方法
- 专利标题： Modulators of lymphocyte activation, Mkk3b compositions and methods of use
- 专利标题（中）： 淋巴细胞活化调节剂，Mkk3b组成和使用方法
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申请号： US10495901申请日： 2002-11-18
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公开(公告)号： US07368257B2公开(公告)日： 2008-05-06
- 发明人: Alan C. Fu , Jun Wu , X. Charlene Liao , Helena Mancebo
- 申请人： Alan C. Fu , Jun Wu , X. Charlene Liao , Helena Mancebo
- 申请人地址： US CA South San Francisco
- 专利权人： Rigel Pharmaceuticals, Incorporated
- 当前专利权人： Rigel Pharmaceuticals, Incorporated
- 当前专利权人地址： US CA South San Francisco
- 代理机构： Klarquist Sparkman LLP
- 国际申请： PCT/US02/36881 WO 20021118
- 国际公布： WO03/044529 WO 20030530
- 主分类号： C12Q1/48
- IPC分类号： C12Q1/48 ; C12Q1/02 ; C12P21/06
摘要：
The present invention provides compositions and methods for modulating lymphocyte activation. Nucleic acids encoding proteins and proteins so encoded which are capable of modulating lymphocyte activation are provided. Compositions and methods for the treatment of disorders related to lymphocyte dysfunction or dysregulation are also provided. Prophylactics and methods for the prevention of such disorders are also provided. Also provided are compositions and methods for diagnostic and prognostic determination of such disorders. Further provided are assays for the identification of bioactive agents capable of modulating lymphocyte activation.
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