发明授权
US07371364B2 Cyclic peptide and imaging compound compositions and uses for targeted imaging and therapy
失效
循环肽和成像化合物组合物和用于靶向成像和治疗的用途
- 专利标题： Cyclic peptide and imaging compound compositions and uses for targeted imaging and therapy
- 专利标题（中）： 循环肽和成像化合物组合物和用于靶向成像和治疗的用途
-
申请号： US10918009申请日： 2004-08-13
-
公开(公告)号： US07371364B2公开(公告)日： 2008-05-13
- 发明人: Chun Li , Wei Wang , Shi Ke
- 申请人： Chun Li , Wei Wang , Shi Ke
- 申请人地址： US TX Austin
- 专利权人： Board of Regents, The University of Texas System
- 当前专利权人： Board of Regents, The University of Texas System
- 当前专利权人地址： US TX Austin
- 代理机构： Baker Botts L.L.P.
- 主分类号： A61K51/00
- IPC分类号： A61K51/00 ; A61K38/00 ; A61K38/12 ; C07K5/00 ; C07K7/00 ; C07K16/00 ; C07K17/00
摘要：
The present invention relates to novel cyclic peptides that may be conjugated with imaging agents, including novel imaging agents. Specifically, it includes c(KRGDf; SEQ ID NO. 3) NIR imaging compositions and novel cyclic HWGFTL (SEQ ID NO. 5) polypeptides which may be used inter alia in NIR, MRI and nuclear imaging as well as therapy. Additionally, the invention includes novel imaging agents, such as TS-ICG derivatives. The invention also relates to methods of making and using such compounds. Such uses include both pre-operative and intraoperative detection of tumor cells and treatment monitoring.
公开/授权文献
信息查询
