发明授权
- 专利标题: Peptide nucleic acids with polyamide-containing backbones
- 专利标题(中): 肽核酸与含聚酰胺的骨架
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申请号: US10154890申请日: 2002-05-23
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公开(公告)号: US07378485B2公开(公告)日: 2008-05-27
- 发明人: Ole Buchardt , Michael Egholm , Peter Eigil Nielsen , Rolf Henrik Berg
- 申请人: Ole Buchardt , Michael Egholm , Peter Eigil Nielsen , Rolf Henrik Berg
- 代理机构: Isis Patent Department
- 优先权: DK0986/91 19910524; DK0987/91 19910524; DK0510/92 19920415
- 主分类号: C07K5/00
- IPC分类号: C07K5/00 ; C12Q1/68 ; A61K38/00
摘要:
A novel class of compounds, known as peptide nucleic acids, bind complementary ssDNA and RNA strands more strongly than a corresponding DNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases attached to a peptide backbone through a suitable linker.
公开/授权文献
- US20030180734A1 Peptide nucleic acids 公开/授权日:2003-09-25
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