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US07384921B2 Polymorphic forms of 6-11 bicyclic ketolide derivatives 有权
6-11双环酮内酯衍生物的多形态

Polymorphic forms of 6-11 bicyclic ketolide derivatives
摘要:
The present invention includes EP-13420 polymorphic crystalline forms: Form I, Form II, Form Ia, and monohydrate and amorphous EP-13420 which posses distinct physical properties. In another embodiment of the present invention, there are provided methods of producing the various polymorphic forms in pure form or in combination with one another. The present invention also provides pharmaceutical compositions and formulations comprising the polymorphic and amorphous forms and methods of treating bacterial infections by administering the pharmaceutical compositions to a subject in need of such treatment.
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