Invention Grant
US07404955B2 Methods of inhibiting or neutralizing TNFα in patients with tissue injury
失效
在组织损伤患者中抑制或中和TNFalpha的方法
- Patent Title: Methods of inhibiting or neutralizing TNFα in patients with tissue injury
- Patent Title (中): 在组织损伤患者中抑制或中和TNFalpha的方法
-
Application No.: US11195589Application Date: 2005-08-02
-
Publication No.: US07404955B2Publication Date: 2008-07-29
- Inventor: Junming Le , Jan Vilcek , Peter Daddona , John Ghrayeb , David Knight , Scott Siegel
- Applicant: Junming Le , Jan Vilcek , Peter Daddona , John Ghrayeb , David Knight , Scott Siegel
- Applicant Address: US PA Malvern US NY New York
- Assignee: Centocor, Inc.,New York University
- Current Assignee: Centocor, Inc.,New York University
- Current Assignee Address: US PA Malvern US NY New York
- Agency: Hamilton, Brook, Smith & Reynolds, P.C.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/24
Abstract:
Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-α (TNFα) and are useful in vivo diagnosis and therapy of a number of TNFα-mediated pathologies and conditions, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of the anti-TNF antibody, or fragment, region or derivative thereof, in immunoassays and immunotherapeutic approaches are provided.
Public/Granted literature
- US20060024310A1 Methods of treating TNFalpha-mediated tissue injury using anti-TNF antibodies and peptides Public/Granted day:2006-02-02
Information query
