发明授权
- 专利标题： V-like domain binding molecules and polynucleotides encoding therefor
- 专利标题（中）： 编码V型结构域结合分子的多核苷酸
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申请号： US11588966申请日： 2006-10-27
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公开(公告)号： US07405288B2公开(公告)日： 2008-07-29
- 发明人: Maria Galanis , Peter John Hudson , Robert Alexander Irving , Stewart Douglas Nuttall
- 申请人： Maria Galanis , Peter John Hudson , Robert Alexander Irving , Stewart Douglas Nuttall
- 申请人地址： AU Queensland
- 专利权人： Diatech Pty. Ltd.
- 当前专利权人： Diatech Pty. Ltd.
- 当前专利权人地址： AU Queensland
- 代理机构： Frommer Lawrence & Haug LLP
- 代理商 Thomas J. Kowalski; Anne-Marie C. Yvon
- 优先权： AUPP2210 19980306
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; C12N15/00 ; C12N1/21 ; C12P21/00
摘要：
The present invention relates to binding moieties comprising at least one monomeric V-like domain (VLD) derived from a non-antibody ligand, the at least one monomeric V-like domain being characterised in that at least one CDR loop structure or part thereof is modified or replaced such that the solubility of the modified VLD is improved when compared with the unmodified VLD.
公开/授权文献
- US20070065431A1 V-like domain binding molecules 公开/授权日：2007-03-22
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