发明授权
- 专利标题: Multiplex data collection and analysis in bioanalyte detection
- 专利标题(中): 生物分析仪检测中的多重数据收集和分析
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申请号: US11216112申请日: 2005-09-01
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公开(公告)号: US07410763B2公开(公告)日: 2008-08-12
- 发明人: Xing Su , Lei Sun , Mineo Yamakawa , Jingwu Zhang , Qing Ma , Tae-Woong Koo , Richard Jones
- 申请人: Xing Su , Lei Sun , Mineo Yamakawa , Jingwu Zhang , Qing Ma , Tae-Woong Koo , Richard Jones
- 申请人地址: US CA Santa Clara
- 专利权人: Intel Corporation
- 当前专利权人: Intel Corporation
- 当前专利权人地址: US CA Santa Clara
- 代理机构: Darby & Darby PC
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; G01N33/53 ; C12M1/00
摘要:
Method and device to collect multiplex data simultaneously in analyte detection and analyze the data by experimentally trained software (machine-learning) is disclosed. Various ways (magnetic particles and microcoils) are disclosed to collect multiple reporter (tag) signals. Multiplex detection can increase the biomolecule analysis efficiency by using small sample size and saving assay reagents and time. Machine learning and data analysis schemes are also disclosed. Multiple affinity binding partners, each labeled by a unique reporter, are contacted with a sample and a green spectrum is taken to detect multiple reporter signals. The spectrum is deconvoluted by experimentally trained software to identify multiple analytes.
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