Invention Grant
- Patent Title: Mass spectrometric methods for detecting mutations in a target nucleic acid
- Patent Title (中): 用于检测靶核酸突变的质谱法
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Application No.: US11432171Application Date: 2006-05-11
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Publication No.: US07419787B2Publication Date: 2008-09-02
- Inventor: Hubert Köster
- Applicant: Hubert Köster
- Applicant Address: US CA San Diego
- Assignee: Sequenom, Inc.
- Current Assignee: Sequenom, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Grant Anderson LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34
Abstract:
Provided herein in certain embodiments are processes that generally include the following steps: amplifying a target nucleic acid molecule; ionizing and volatilizing the amplification product and analyzing the ionized and volatilized product by mass spectrometry. In some embodiments the amplification product is a natural nucleic acid and detection of the target nucleotide sequence by mass spectrometry indicates the presence of the target nucleotide sequence in the biological sample.
Public/Granted literature
- US20060223105A1 Mass spectrometric methods for detecting mutations in a target nucleic acid Public/Granted day:2006-10-05
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