发明授权
- 专利标题: Agent for preventing or treating neuropathy
- 专利标题(中): 神经病防治药
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申请号: US10532667申请日: 2003-10-30
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公开(公告)号: US07423159B2公开(公告)日: 2008-09-09
- 发明人: Yu Momose , Nozomu Sakai , Tsuyoshi Maekawa , Masatoshi Hazama , Toru Kawamura
- 申请人: Yu Momose , Nozomu Sakai , Tsuyoshi Maekawa , Masatoshi Hazama , Toru Kawamura
- 申请人地址: JP Osaka
- 专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人地址: JP Osaka
- 代理机构: Wenderoth, Lind & Ponack, L.L.P.
- 优先权: JP2002-320153 20021101
- 国际申请: PCT/JP03/13901 WO 20031030
- 国际公布: WO2004/039365 WO 20040513
- 主分类号: C07D213/10
- IPC分类号: C07D213/10
摘要:
The present invention provides an agent for preventing or treating neuropathy having superior action and low toxicity. This agent comprises a compound represented by the formula: wherein ring A is a 5-membered aromatic heterocycle containing 2 or more nitrogen atoms, which may further have substituent(s); B is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; X is a divalent acyclic hydrocarbon group; Z is —O—, —S—, —NR2—, —CONR2— or —NR2CO— (R2 is a hydrogen atom or an optionally substituted alkyl group); Y is a bond or a divalent acyclic hydrocarbon group; R1 is an optionally substituted cyclic group, an optionally substituted amino group or an optionally substituted acyl group, provided that when the 5-membered aromatic heterocycle represented by ring A is imidazole, then Z should not be —O—, or a salt thereof.
公开/授权文献
- US20060004069A1 Agent for preventing or treating neuropathy 公开/授权日:2006-01-05