发明授权
- 专利标题： Vaccines against West Nile Virus
- 专利标题（中）： 针对西尼罗病毒的疫苗
-
申请号： US11110517申请日： 2005-04-20
-
公开(公告)号： US07425437B2公开(公告)日： 2008-09-16
- 发明人: Alphonsus G. C. M. UytdeHaag , Govert Johan Schouten , Jaap Goudsmit
- 申请人： Alphonsus G. C. M. UytdeHaag , Govert Johan Schouten , Jaap Goudsmit
- 申请人地址： NL Leiden
- 专利权人： Crucell Holland B.V.
- 当前专利权人： Crucell Holland B.V.
- 当前专利权人地址： NL Leiden
- 代理机构： TraskBritt
- 主分类号： C12N7/00
- IPC分类号： C12N7/00 ; C12N7/02 ; C12N7/06
摘要：
The present invention relates to novel vaccines containing (whole-inactivated) West Nile Viruses and/or West Nile viral proteins derived therefrom, produced on human cells, wherein the human cells comprise a sequence encoding at least one early region-1 (E1) gene product of an adenovirus. The cells are preferably cultured in suspension to very high densities and under serum-free conditions. Herein, it is disclosed that use of such cells results in high titers of West Nile Virus produced.
公开/授权文献
- US20080206279A9 VACCINES AGAINST WEST NILE VIRUS 公开/授权日：2008-08-28
信息查询
