An information processing system includes a branch target buffer (BTB) comprising the last next address for the instruction and for receiving an indirect instruction address and providing a BTB predicted target; and next branch target table (NBTT) for storing potential branch targets based on a history of the branch and for providing an NBTT when the a BTB predicted target is not successful. In another embodiment a system comprising a plurality of branch prediction resources dynamically predicts the best resource appropriate for a branch. The method includes predicting a target branch for an indirect instruction address using a resource chosen among the plurality of branch prediction resources; and selectively inhibiting updates of the branch prediction resources whose prediction accuracy does not meet a threshold.