Invention Grant
- Patent Title: Thiazole derivatives
- Patent Title (中): 噻唑衍生物
-
Application No.: US11505321Application Date: 2006-08-17
-
Publication No.: US07442715B2Publication Date: 2008-10-28
- Inventor: Akira Nagashima , Takayuki Inoue , Mitsuru Ohkubo , Kousei Yoshihara , Takashi Tojo , Masataka Morita
- Applicant: Akira Nagashima , Takayuki Inoue , Mitsuru Ohkubo , Kousei Yoshihara , Takashi Tojo , Masataka Morita
- Applicant Address: JP Tokyo
- Assignee: Astellas Pharma Inc.
- Current Assignee: Astellas Pharma Inc.
- Current Assignee Address: JP Tokyo
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, P.C.
- Main IPC: A61K31/427
- IPC: A61K31/427

Abstract:
A compound of the formula (I): R1—NH—X—Y-Z (I) wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof useful as a vascular adhesion protein-1 (VAP-1) inhibitor, a pharmaceutical composition, a method for preventing or treating a VAP-1 associated disease, especially macular edema, which method includes administering an effective amount of the compound or a pharmaceutically acceptable salt thereof to a mammal, and the like.
Public/Granted literature
- US20060276521A1 Thiazole derivatives Public/Granted day:2006-12-07
Information query
IPC分类: