发明授权
- 专利标题： Polymorphic forms of sertraline hydrochloride
- 专利标题（中）： 盐酸舍曲林的多形态
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申请号： US11101860申请日： 2005-04-08
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公开(公告)号： US07442838B2公开(公告)日： 2008-10-28
- 发明人: Paul Adriaan Van Der Schaaf , Franz Schwarzenbach , Hans Jürg Kirner , Martin Szelagiewicz , Claudia Marcolli , Andreas Burkhard
- 申请人： Paul Adriaan Van Der Schaaf , Franz Schwarzenbach , Hans Jürg Kirner , Martin Szelagiewicz , Claudia Marcolli , Andreas Burkhard
- 申请人地址： US NY Tarrytown
- 专利权人： Ciba Specialty Chemicals Corp.
- 当前专利权人： Ciba Specialty Chemicals Corp.
- 当前专利权人地址： US NY Tarrytown
- 代理商 Mervin G. Wood
- 优先权： EP99810981 19991029
- 主分类号： C07C211/42
- IPC分类号： C07C211/42
摘要：
Sertraline hydrochloride polymorphic form II is conveniently prepared by adding hydrogen chloride to solution of sertraline free amine in a ketone. In preferred processes, the solution of sertraline free amine seeded with some crystals of polymorphic form II and/or the solution is heated before addition of the hydrogen chloride.
公开/授权文献
- US20050197404A1 Polymorphic forms of sertraline hydrochloride 公开/授权日：2005-09-08
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