发明授权
- 专利标题： Assays for assembly of Ebola virus nucleocapsids
- 专利标题（中）： 用于组装埃博拉病毒核衣壳的分析
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申请号： US11031921申请日： 2005-01-07
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公开(公告)号： US07449190B2公开(公告)日： 2008-11-11
- 发明人: Gary Nabel , Yue Huang
- 申请人： Gary Nabel , Yue Huang
- 申请人地址： US DC Washington
- 专利权人： The United States of America as represented by the Department of Health and Human Services
- 当前专利权人： The United States of America as represented by the Department of Health and Human Services
- 当前专利权人地址： US DC Washington
- 代理机构： Knobbe Martens Olson & Bear LLP
- 主分类号： A61K39/00
- IPC分类号： A61K39/00
摘要：
The present invention relates to assays for the identification of compounds that inhibit assembly of NP, VP35, and VP24, or inhibit the glycosylation of NP, required for nucleocapsid formation, for use as anti-viral agents. The invention also relates to assays for the identification of compounds that block glycosylation of proteins having a glycosylation domain that is substantially homologous to a glycosylation domain of NP required for polymerization. The invention further relates to pseudoparticles for presentation of antigens or antigenic epitopes for immunogenic or vaccination purposes.
公开/授权文献
- US20050180993A1 Assays for assembly of ebola virus nucleocapsids 公开/授权日：2005-08-18
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