Invention Grant
- Patent Title: Diaminopyrimidinecarboxamide derivative
- Patent Title (中): 二氨基嘧啶甲酰胺衍生物
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Application No.: US10518043Application Date: 2003-06-26
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Publication No.: US07449456B2Publication Date: 2008-11-11
- Inventor: Shinya Nagashima , Hiroshi Nagata , Masahiro Iwata , Masaki Yokota , Hiroyuki Moritomo , Eiichi Nakai , Sadao Kuromitsu , Keiko Ohga , Makoto Takeuchi
- Applicant: Shinya Nagashima , Hiroshi Nagata , Masahiro Iwata , Masaki Yokota , Hiroyuki Moritomo , Eiichi Nakai , Sadao Kuromitsu , Keiko Ohga , Makoto Takeuchi
- Applicant Address: JP Tokyo
- Assignee: Astellas Pharma, Inc.
- Current Assignee: Astellas Pharma, Inc.
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2002-190959 20020628
- International Application: PCT/JP03/08129 WO 20030626
- International Announcement: WO2004/002964 WO 20040108
- Main IPC: C07D239/48
- IPC: C07D239/48 ; A61K31/506

Abstract:
A compound which may be used for the prevention or treatment of respiratory diseases in which STAT 6 is concerned, particularly asthma, chronic obstructive pulmonary disease and the like is provided.A pyrimidine derivative or a salt thereof, which has an arylamino or arylethylamino group which may be substituted with a specified substituent, at the 2-position, amino group substituted with benzyl group or the like, at the 4-position, and carbamoyl group which may be substituted, at the 5-position, is provided.
Public/Granted literature
- US20050272753A1 Diaminopyrimidinecarboxa mide derivative Public/Granted day:2005-12-08
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