发明授权
- 专利标题： Liver protection compounds of the cyclohexenone type from Antrodia camphorata
- 专利标题（中）： 来自樟芝的环己烯酮类型的肝保护化合物
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申请号： US11902599申请日： 2007-09-24
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公开(公告)号： US07456225B1公开(公告)日： 2008-11-25
- 发明人: Sheng-Yun Liu , Wu-Che Wen , Mao-Tien Kuo
- 申请人： Sheng-Yun Liu , Wu-Che Wen , Mao-Tien Kuo
- 申请人地址： TW Taipei Hsien
- 专利权人： Golden Biotechnology Corporation
- 当前专利权人： Golden Biotechnology Corporation
- 当前专利权人地址： TW Taipei Hsien
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP
- 优先权： TW96121548A 20070614
- 主分类号： A61K31/12
- IPC分类号： A61K31/12 ; C07C49/543 ; C07C49/557
摘要：
The present invention relates to a compound of Antrodia camphorata used for liver protection, in particular to an extract, 4-hydroxy-2,3-dimethoxy-6-methyl-5(3,7,11-trimethyl-dodeca-2,6,10-trienyl)-cyclohex-2-enone which is isolated from Antrodia camphorata. The cyclohexenone compound according to the invention helps to alleviate liver injury and fibrosis induced by chemicals and reduces the levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST). By increasing the contents of glutathione peroxidase (GSHPx) and catalase (CAT), cyclohexenone further decreases the liver damage and the oxidative pressure caused by free radicals, enhances the antioxidant ability and achieves the purposed of liver protection.
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