发明授权
US07462724B2 Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors
有权
取代的1H-苯并咪唑-4-甲酰胺是有效的PARP抑制剂
- 专利标题： Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors
- 专利标题（中）： 取代的1H-苯并咪唑-4-甲酰胺是有效的PARP抑制剂
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申请号： US11560166申请日： 2006-11-15
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公开(公告)号： US07462724B2公开(公告)日： 2008-12-09
- 发明人: Thomas D. Penning , Sheela A. Thomas , Gui-Dong Zhu , Jianchun Gong , Vincent L. Giranda , Viraj B. Gandhi
- 申请人： Thomas D. Penning , Sheela A. Thomas , Gui-Dong Zhu , Jianchun Gong , Vincent L. Giranda , Viraj B. Gandhi
- 申请人地址： US IL Abbott Park
- 专利权人： Abbott Laboratories
- 当前专利权人： Abbott Laboratories
- 当前专利权人地址： US IL Abbott Park
- 代理商 Rachel A. Polster
- 主分类号： A61K31/4184
- IPC分类号： A61K31/4184 ; C07D235/18
摘要：
Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of Formula (I), and methods of inhibiting the PARP enzyme comprising compounds of Formula (I).
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