发明授权
US07473787B2 Bicyclic [3.1.0] derivatives as glycine transporter inhibitors
有权
双环[3.1.0]衍生物作为甘氨酸转运蛋白抑制剂
![Bicyclic [3.1.0] derivatives as glycine transporter inhibitors](/docs/US/2009-01-06/US07473787B2/abs.jpg.600x600.jpg)
- 专利标题： Bicyclic [3.1.0] derivatives as glycine transporter inhibitors
- 专利标题（中）： 双环[3.1.0]衍生物作为甘氨酸转运蛋白抑制剂
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申请号： US10964931申请日： 2004-10-14
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公开(公告)号： US07473787B2公开(公告)日： 2009-01-06
- 发明人: Stanton McHardy , John A. Lowe
- 申请人： Stanton McHardy , John A. Lowe
- 申请人地址： US NY New York
- 专利权人： Pfizer Inc
- 当前专利权人： Pfizer Inc
- 当前专利权人地址： US NY New York
- 代理商 Steve T. Zelson; Garth Butterfield; Sandra Kim
- 主分类号： C07D209/52
- IPC分类号： C07D209/52
![Bicyclic [3.1.0] derivatives as glycine transporter inhibitors](/abs-image/US/2009/01/06/US07473787B2/abs.jpg.150x150.jpg)
摘要：
The present invention relates to a series of substituted bicyclic[3.1.0]amines of the Formula I: wherein A, B, D, Q, V, W, X, Y, Z, R2, R3, R4, R5, R14, R15, R30. o, p, s,t and q are as defined in the specification, their pharmaceutically acceptable salts, pharmaceutical compositions thereof, and their use for the enhancement of cognition and the treatment of the positive and negative symptoms of schizophrenia and other psychoses in mammals, including humans.
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