发明授权
US07491724B2 Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases 有权
取代的环状异羟肟酸盐作为基质金属蛋白酶的抑制剂

Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases
摘要:
The present invention provides compounds of the formula I: its enantiomers, diastereomers, racemic mixtures thereof, prodrugs, crystalline forms, non-crystalline forms, amorphous forms thereof, solvates thereof, metabolites thereof, and pharmaceutically acceptable salts, wherein the ring A substituent groups are fully defined in the following disclosure. The compounds of formula I are inhibitors of metalloproteases such as matrix metalloproteases and sheddases, and are useful in treating diseases such as rheumatoid arthritis, psoriasis, neoplastic diseases, allergies and all those diseases wherein inhibition of MMPs is desirable.
信息查询
0/0