Invention Grant
- Patent Title: Crystal structure of liganded cFMS kinase domain
- Patent Title (中): 配体cFMS激酶结构域的晶体结构
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Application No.: US11430342Application Date: 2006-05-09
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Publication No.: US07491731B2Publication Date: 2009-02-17
- Inventor: Holly Kathleen Emerson , David Lee Musso , Stanley Dawes Chamberlain , Gregory Edward Peckham
- Applicant: Holly Kathleen Emerson , David Lee Musso , Stanley Dawes Chamberlain , Gregory Edward Peckham
- Applicant Address: US PA Philadelphia
- Assignee: SmithKline Beecham Corporation
- Current Assignee: SmithKline Beecham Corporation
- Current Assignee Address: US PA Philadelphia
- Agent Kathryn L. Coulter
- Main IPC: C07D239/49
- IPC: C07D239/49 ; A61K31/505
Abstract:
A crystal structure of the cfms kinase domain, co-crystal structure with a bound small molecule, as well as methods of using the same in the discovery of cfms inhibitors and in the treatment of diseases mediated by inappropriate cfms activity.
Public/Granted literature
- US20070010540A1 Crystal structure of liganded cFMS kinase domain Public/Granted day:2007-01-11
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