发明授权
- 专利标题: Antiangiogenic agents
- 专利标题(中): 抗血管生成剂
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申请号: US11077977申请日: 2005-03-11
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公开(公告)号: US07498322B2公开(公告)日: 2009-03-03
- 发明人: Gregory E. Agoston , Jamshed H. Shah , Lita Suwandi , Theresa M. LaVallee , Anthony M. Treston
- 申请人: Gregory E. Agoston , Jamshed H. Shah , Lita Suwandi , Theresa M. LaVallee , Anthony M. Treston
- 申请人地址: US MD Rockville
- 专利权人: EntreMed, Inc.
- 当前专利权人: EntreMed, Inc.
- 当前专利权人地址: US MD Rockville
- 代理机构: King & Spalding LLP
- 主分类号: A61K31/56
- IPC分类号: A61K31/56 ; C07J1/00
摘要:
Compositions and methods for treating mammalian diseases or conditions characterized by undesirable angiogenesis by administering an effective amount of a compound of the formulae: wherein Ra is selected from —OCH3, —OCH2CH3 or —CCCH3; and Z is selected from >C(H)—OH, >C(H)—O-alkyl, >C(H)—O-sulfamate, where alkyl is a linear, branched and/or cyclic hydrocarbon chain comprising 1 to 10 carbons.
公开/授权文献
- US20050203075A1 Antiangiogenic agents 公开/授权日:2005-09-15
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