发明授权
- 专利标题: Method for producing and cleaving a fusion proteins with an n-terminal chymosin pro-peptide
- 专利标题(中): 用n末端凝乳酶原肽生产和切割融合蛋白的方法
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申请号: US09402488申请日: 1998-04-23
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公开(公告)号: US07501265B1公开(公告)日: 2009-03-10
- 发明人: Maurice Moloney , Joenel Alcantara , Gijs Van Rooijen
- 申请人: Maurice Moloney , Joenel Alcantara , Gijs Van Rooijen
- 申请人地址: CA Calgary, Alberta
- 专利权人: SemBioSys Genetics Inc.
- 当前专利权人: SemBioSys Genetics Inc.
- 当前专利权人地址: CA Calgary, Alberta
- 代理机构: Bereskin & Parr
- 代理商 Micheline Gravelle
- 国际申请: PCT/CA98/00398 WO 19980423
- 国际公布: WO98/49326 WO 19981105
- 主分类号: C12P21/04
- IPC分类号: C12P21/04 ; C12P21/06 ; C12P21/00 ; C12N9/50
摘要:
An improved method for recovering recombinantly produced polypeptides is described. The method involves expressing the recombinant polypeptide as a fusion protein with a pro-peptide. The pro-peptide-polypeptide fusion protein can be cleaved and the recombinant polypeptide released under the appropriate conditions.
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