Invention Grant
US07501554B2 Transgenic animals producing low-lactose milk and newly identified human small intestinal extracellular lactase-phlorizin hydrolase (ecLPH) gene
有权
产生低乳糖乳和新鉴定的人小肠细胞外乳糖酶 - 根皮苷水解酶（ecLPH）基因的转基因动物
- Patent Title: Transgenic animals producing low-lactose milk and newly identified human small intestinal extracellular lactase-phlorizin hydrolase (ecLPH) gene
- Patent Title (中): 产生低乳糖乳和新鉴定的人小肠细胞外乳糖酶 - 根皮苷水解酶（ecLPH）基因的转基因动物
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Application No.: US11434332Application Date: 2006-05-15
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Publication No.: US07501554B2Publication Date: 2009-03-10
- Inventor: Chuan-Mu Chen , Winston T. K. Cheng , Hsiao-Ling Chen
- Applicant: Chuan-Mu Chen , Winston T. K. Cheng , Hsiao-Ling Chen
- Applicant Address: TW Taichung
- Assignee: National Chung Hsing University
- Current Assignee: National Chung Hsing University
- Current Assignee Address: TW Taichung
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Main IPC: A01K67/027
- IPC: A01K67/027 ; C12N15/00
Abstract:
The invention provides a transgenic animal producing low-lactose milk, which is transformed with a gene encoding an extracellular lactase-hydrolyzing enzyme cloned from a human small intestinal cDNA library. The invention also provides a new extracellular lactase-phlorizin hydrolase (ecLPH) gene that can express human lactase-hydrolyzing enzyme in the mammary gland of animals. The invention can be used in the production of low-lactose milk.
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