发明授权
- 专利标题： Benzamide modulators of metabotropic glutamate receptors
- 专利标题（中）： 代谢型谷氨酸受体的苯甲酰胺调节剂
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申请号： US10550968申请日： 2004-03-22
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公开(公告)号： US07507836B2公开(公告)日： 2009-03-24
- 发明人: Mark E. Duggan , Craig W. Lindsley , David D. Wisnoski
- 申请人： Mark E. Duggan , Craig W. Lindsley , David D. Wisnoski
- 申请人地址： US NJ Rahway
- 专利权人： Merck & Co. Inc.
- 当前专利权人： Merck & Co. Inc.
- 当前专利权人地址： US NJ Rahway
- 代理商 J. Eric Thies; William Krovatin
- 国际申请： PCT/US2004/008627 WO 20040322
- 国际公布： WO2004/087048 WO 20041014
- 主分类号： C07D209/48
- IPC分类号： C07D209/48 ; C07C233/05 ; A61K31/40 ; A61K31/165
摘要：
The present invention is directed to compounds which are allosteric modulators of metabotropic glutamate receptors, including the mGluR5 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.
公开/授权文献
- US20060235069A1 Benzamide modulators of metabotropic glutamate receptors 公开/授权日：2006-10-19
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