发明授权
- 专利标题： Apparatus and method for preparing microparticles using in-line solvent extraction
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申请号： US11826533申请日： 2007-07-16
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公开(公告)号： US07510730B2公开(公告)日： 2009-03-31
- 发明人: Shawn L. Lyons , Steven G. Wright
- 申请人： Shawn L. Lyons , Steven G. Wright
- 申请人地址： US MA Cambridge
- 专利权人： Alkermes, Inc.
- 当前专利权人： Alkermes, Inc.
- 当前专利权人地址： US MA Cambridge
- 代理机构： Covington & Burling LLP
- 代理商 Andrea G. Reister
- 主分类号： A61K9/50
- IPC分类号： A61K9/50 ; B01F15/02
摘要：
Apparatus and method for preparing microparticles using in-line solvent extraction. An emulsion is formed by combining two phases in a static mixer. The emulsion is combined with an extraction liquid in a blending static mixer. The outflow of the blending static mixer is combined with additional extraction liquid. The additional extraction liquid and the outflow of the blending static mixer can be combined in a vessel, or through the use of a static mixer manifold that includes a plurality of static mixers.
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