发明授权
- 专利标题： Aryl ureido benzoic acid derivatives and their use
- 专利标题（中）： 芳基脲基苯甲酸衍生物及其用途
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申请号： US10535683申请日： 2003-11-10
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公开(公告)号： US07521480B2公开(公告)日： 2009-04-21
- 发明人: Jon Valgeirsson , Elsebet Østergaard Nielsen , Dan Peters
- 申请人： Jon Valgeirsson , Elsebet Østergaard Nielsen , Dan Peters
- 申请人地址： DK Ballerup
- 专利权人： Neurosearch
- 当前专利权人： Neurosearch
- 当前专利权人地址： DK Ballerup
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP
- 优先权： DK200201803 20021121
- 国际申请： PCT/DK03/00768 WO 20031110
- 国际公布： WO2004/046090 WO 20040603
- 主分类号： A61K31/135
- IPC分类号： A61K31/135 ; C07C273/00 ; C07C275/00
摘要：
This invention relates to novel aryl ureido benzoic acid derivatives useful as selective and non-competitive antagonists of the ionotropic GluR5 receptor. Due to their biological activity, the aryl ureido derivatives of the invention are considered useful for treating diseases that are responsive to modulation of an aspartate or a glutamate receptor. Moreover the invention provides chemical compounds for use according to the invention, as well as pharmaceutical compositions comprising the chemical compounds, and methods of treating diseases or disorders or conditions responsive to modulation of an aspartate or a glutamate receptor.
公开/授权文献
- US20060069255A1 Novel aryl ureido benzoic acid derivatives and their use 公开/授权日：2006-03-30
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