Invention Grant
US07524965B2 Dialkylphenyl compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity
有权
具有β2肾上腺素能受体激动剂和毒蕈碱受体拮抗剂活性的二烷基苯基化合物
- Patent Title: Dialkylphenyl compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity
- Patent Title (中): 具有β2肾上腺素能受体激动剂和毒蕈碱受体拮抗剂活性的二烷基苯基化合物
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Application No.: US11789300Application Date: 2007-04-24
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Publication No.: US07524965B2Publication Date: 2009-04-28
- Inventor: Pierre-Jean Colson , Adam D. Hughes , Craig Husfeld , Mathai Mammen , Miroslav Rapta
- Applicant: Pierre-Jean Colson , Adam D. Hughes , Craig Husfeld , Mathai Mammen , Miroslav Rapta
- Applicant Address: US CA South San Francisco
- Assignee: Theravance, Inc.
- Current Assignee: Theravance, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Jeffrey A. Hagenah
- Main IPC: C07D211/40
- IPC: C07D211/40 ; A61K31/445
Abstract:
This invention relates to compounds of formula I: wherein R1 and R2 are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The invention also relates to pharmaceutical compositions and combinations comprising such compounds, processes and intermediates for preparing such compounds, and methods of using such compound to, for example, treat pulmonary disorders, such as chronic obstructive pulmonary disease and asthma.
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