发明授权
US07528243B2 Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of breast cancer
有权
核苷酸和氨基酸序列,以及其用于诊断乳腺癌的测定和方法
- 专利标题: Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of breast cancer
- 专利标题(中): 核苷酸和氨基酸序列,以及其用于诊断乳腺癌的测定和方法
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申请号: US11711827申请日: 2007-02-28
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公开(公告)号: US07528243B2公开(公告)日: 2009-05-05
- 发明人: Amir Toporik , Dvir Dahary , Rotem Sorek , Sarah Pollock , Zurit Levine , Pinchas Akiva , Alexander Diber , Amit Novik , Osnat Sella-Tavor , Michal Ayalon-Soffer , Shira Walach , Shirley Sameah-Greenwald , Ronen Shemesh , Naomi Keren , Maxim Shklar
- 申请人: Amir Toporik , Dvir Dahary , Rotem Sorek , Sarah Pollock , Zurit Levine , Pinchas Akiva , Alexander Diber , Amit Novik , Osnat Sella-Tavor , Michal Ayalon-Soffer , Shira Walach , Shirley Sameah-Greenwald , Ronen Shemesh , Naomi Keren , Maxim Shklar
- 申请人地址: IL Tel Aviv
- 专利权人: Compugen Ltd
- 当前专利权人: Compugen Ltd
- 当前专利权人地址: IL Tel Aviv
- 代理机构: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo PC
- 代理商 Ivor R. Elrifi; David E. Johnson
- 主分类号: C07H21/02
- IPC分类号: C07H21/02 ; C07H21/04
摘要:
Novel markers for breast cancer that are both sensitive and accurate. These markers are overexpressed in breast cancer specifically, as opposed to normal breast tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of breast cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between breast cancer and non-cancerous states.
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