发明授权
- 专利标题： Process and intermediates for preparing emtricitabine
- 专利标题（中）： 制备恩曲他滨的方法和中间体
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申请号： US10550718申请日： 2004-03-19
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公开(公告)号： US07534885B2公开(公告)日： 2009-05-19
- 发明人: Giorgio Bertolini , Maurizio Deleo , Marco Frigerio , Massimo Losa , Maurizio Velati
- 申请人： Giorgio Bertolini , Maurizio Deleo , Marco Frigerio , Massimo Losa , Maurizio Velati
- 申请人地址： IT Milan
- 专利权人： Archimica S.r.l.
- 当前专利权人： Archimica S.r.l.
- 当前专利权人地址： IT Milan
- 代理机构： ProPat, L.L.C.
- 优先权： ITMI2003A0578 20030324
- 国际申请： PCT/IB2004/000924 WO 20040319
- 国际公布： WO2004/085432 WO 20041007
- 主分类号： C07D411/04
- IPC分类号： C07D411/04 ; A61K31/513 ; A61K31/12
摘要：
A process is disclosed for the stereo-selective preparation of emtricitabine, which allows the desired product to be obtained in good yield and without the use of chromatographic techniques. The process for the production of emtricitabine of the formula (Ia) is characterized by the formation and isolation of intermediate compounds of formula (XIa) in salified form. Emtricitabine is a known antiviral drug.
公开/授权文献
- US20060189805A1 Process and intermediates for preparing emtricitabine 公开/授权日：2006-08-24
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