发明授权
- 专利标题: Glycopeptide conjugates and uses thereof
- 专利标题(中): 糖肽缀合物及其用途
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申请号: US10898410申请日: 2004-07-23
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公开(公告)号: US07550146B2公开(公告)日: 2009-06-23
- 发明人: Samuel J. Danishefsky , Dalibor Sames , Samuel Hintermann , Peter Glunz , Govindaswami Ragupathi , Philip O. Livingston , Kenneth O. Lloyd , Valery Kudryashov
- 申请人: Samuel J. Danishefsky , Dalibor Sames , Samuel Hintermann , Peter Glunz , Govindaswami Ragupathi , Philip O. Livingston , Kenneth O. Lloyd , Valery Kudryashov
- 申请人地址: US NY New York
- 专利权人: Sloan-Kettering Institute For Cancer Research
- 当前专利权人: Sloan-Kettering Institute For Cancer Research
- 当前专利权人地址: US NY New York
- 代理机构: Choate, Hall & Stewart LLP
- 代理商 C. Hunter Baker
- 主分类号: A61K38/14
- IPC分类号: A61K38/14 ; A61K39/385 ; C07K9/00
摘要:
The present invention provides novel glycoconjugates such as glycopeptides, as well as convergent methods for the synthesis thereof. An exemplary preparative approach is exemplified by the synthesis of the mucin motif commonly found on epithelial tumor cell surfaces. The present invention further provides compositions and methods of treating cancer using the glycoconjugates of the invention.
公开/授权文献
- US20050222398A1 Glycopeptide conjugates and uses thereof 公开/授权日:2005-10-06
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