A light scattering sensing system and method. In one embodiment, the system includes a sample branch configured to collect light signals backscattered from scattering centers contained in a coherence volume of a medium under evaluation, the sample branch including a multi-mode optical waveguide. In one embodiment, the method includes radiating low-coherence light into a scattering medium using a multi-mode optical waveguide, and collecting light signals backscattered by the scattering centers and light reflected by an end surface of the multi-mode optical waveguide using the multi-mode optical waveguide.