Invention Grant
US07557120B2 Aminocyclopentyl fused heterotricylicamide modulators of chemokine receptor activity
失效
氨基环戊烯基稠合异酰胺调节剂的趋化因子受体活性
- Patent Title: Aminocyclopentyl fused heterotricylicamide modulators of chemokine receptor activity
- Patent Title (中): 氨基环戊烯基稠合异酰胺调节剂的趋化因子受体活性
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Application No.: US10543794Application Date: 2004-02-23
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Publication No.: US07557120B2Publication Date: 2009-07-07
- Inventor: Stephen D. Goble , Alexander Pasternak , Cheng Tang , Changyou Zhou , Lihu Yang
- Applicant: Stephen D. Goble , Alexander Pasternak , Cheng Tang , Changyou Zhou , Lihu Yang
- Applicant Address: US NJ Rahway
- Assignee: Merck & Co., Inc.
- Current Assignee: Merck & Co., Inc.
- Current Assignee Address: US NJ Rahway
- Agent James L. McGinnis; Mark R. Daniel
- International Application: PCT/US2004/005297 WO 20040223
- International Announcement: WO2004/076411 WO 20040910
- Main IPC: A61K31/437
- IPC: A61K31/437 ; C07D471/02 ; C07D471/14
Abstract:
The present invention is directed to compounds of formulae (I and II)(wherein A, D, E, X, l, m, n and R1 through R18 are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.
Public/Granted literature
- US20070004714A1 Aminocyclopentyl fused heterotricylicamide modulators of chemokine receptor activity Public/Granted day:2007-01-04
Information query
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