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发明授权
US07560457B2 Rapamycin analogues and the uses thereof in the treatment of neurological, proliferative, and inflammatory disorders 失效
雷帕霉素类似物及其在治疗神经，增殖和炎性疾病中的用途

Rapamycin analogues and the uses thereof in the treatment of neurological, proliferative, and inflammatory disorders
摘要：
The present invention provides compounds of the following structure, wherein R1, R2, R4, R4′, R6, R7, and R15 are defined above: These compounds are useful in treating neurological disorders or complications due to stroke or head injury; benign or malignant neoplastic disease, carcinomas and adenocarcinomas; proliferative disorders; and inflammatory disorders. The compounds are therefore useful as neuroprotective and neuroregenerative, anti-proliferative, and anti-inflammatory agents.
摘要（中）：

本发明提供以下结构的化合物，其中R 1，R 2，R 4，R 4'，R 6，R 7和R 15如上所定义：这些化合物可用于治疗由卒中或头部损伤引起的神经系统疾病或并发症; 良性或恶性肿瘤性疾病，癌和腺癌; 增生性疾病; 和炎症性疾病。 因此，这些化合物可用作神经保护和神经再生，抗增殖和抗炎剂。

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