Invention Grant
US07569586B2 Compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity
有权
具有β2肾上腺素能受体激动剂和毒蕈碱受体拮抗剂活性的化合物
- Patent Title: Compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity
- Patent Title (中): 具有β2肾上腺素能受体激动剂和毒蕈碱受体拮抗剂活性的化合物
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Application No.: US11204263Application Date: 2005-08-15
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Publication No.: US07569586B2Publication Date: 2009-08-04
- Inventor: Mathai Mammen , Trevor Mischki , Adam Hughes , Yu-Hua Ji
- Applicant: Mathai Mammen , Trevor Mischki , Adam Hughes , Yu-Hua Ji
- Applicant Address: US CA South San Francisco
- Assignee: Theravance, Inc.
- Current Assignee: Theravance, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Jeffrey A. Hagenah
- Main IPC: A61K31/445
- IPC: A61K31/445

Abstract:
This invention provides compounds of formula I: wherein R1, R2, R3, R4,R5, R6, R7, R8a, R8b, W, a, b, c and m are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The compounds of this invention possess both β2 adrenergic receptor agonist and muscarinic receptor antagonist activity. Accordingly, such compounds are expected to be useful as therapeutic agents for treating pulmonary disorders, such as chronic obstructive pulmonary disease and asthma.
Public/Granted literature
- US20060035933A1 Compounds having beta adrenergic receptor agonist and muscarinic receptor antagonist activity Public/Granted day:2006-02-16
Information query
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