Invention Grant
US07569586B2 Compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity 有权
具有β2肾上腺素能受体激动剂和毒蕈碱受体拮抗剂活性的化合物

Compounds having β2 adrenergic receptor agonist and muscarinic receptor antagonist activity
Abstract:
This invention provides compounds of formula I: wherein R1, R2, R3, R4,R5, R6, R7, R8a, R8b, W, a, b, c and m are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The compounds of this invention possess both β2 adrenergic receptor agonist and muscarinic receptor antagonist activity. Accordingly, such compounds are expected to be useful as therapeutic agents for treating pulmonary disorders, such as chronic obstructive pulmonary disease and asthma.
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