发明授权
US07572624B2 DNA chip comprising a microarray made of an microelectrode system
有权
DNA芯片包括由微电极系统制成的微阵列
- 专利标题: DNA chip comprising a microarray made of an microelectrode system
- 专利标题(中): DNA芯片包括由微电极系统制成的微阵列
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申请号: US10539817申请日: 2003-12-15
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公开(公告)号: US07572624B2公开(公告)日: 2009-08-11
- 发明人: Walter Gumbrecht , Konrad Mund , Meinrad Schienle , Roland Thewes
- 申请人: Walter Gumbrecht , Konrad Mund , Meinrad Schienle , Roland Thewes
- 申请人地址: DE Munich
- 专利权人: Siemens Aktiengesellschaft
- 当前专利权人: Siemens Aktiengesellschaft
- 当前专利权人地址: DE Munich
- 代理机构: Harness, Dickey & Pierce, P.L.C.
- 优先权: DE10259820 20021219
- 国际申请: PCT/DE03/04127 WO 20031215
- 国际公布: WO2004/057334 WO 20040708
- 主分类号: C12M1/34
- IPC分类号: C12M1/34 ; C12M3/00
摘要:
A DNA chip includes a carrier and a microarray of spots containing immobilised catcher molecules which are arranged on the carrier. Each spot contains a microelectrode system for the impedance spectroscopic detection of binding events occurring between the catcher molecules and target molecules of an analyte solution applied to the spots. The microelectrode system has a pair of polarisation electrodes in order to produce an alternating electromagnetic field and a pair of sensor electrodes for measuring a voltage drop in the analyte.
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