发明授权
- 专利标题: Azabicyclic compounds, a process for their preparation and pharmaceutical compositions containing them
- 专利标题(中): 氮杂双环化合物,其制备方法和含有它们的药物组合物
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申请号: US10589831申请日: 2005-02-20
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公开(公告)号: US07576120B2公开(公告)日: 2009-08-18
- 发明人: Patrick Casara , Anne-Marie Chollet , Alain Dhainaut , Lionel Bert , Pierre Lestage , Brian Lockhart
- 申请人: Patrick Casara , Anne-Marie Chollet , Alain Dhainaut , Lionel Bert , Pierre Lestage , Brian Lockhart
- 申请人地址: FR Suresnes Cedex
- 专利权人: Les Laboratoires Servier
- 当前专利权人: Les Laboratoires Servier
- 当前专利权人地址: FR Suresnes Cedex
- 代理机构: Hueschen and Sage
- 优先权: FR0401690 20040220
- 国际申请: PCT/FR2005/000382 WO 20050220
- 国际公布: WO2005/089747 WO 20050929
- 主分类号: A61K31/40
- IPC分类号: A61K31/40 ; C07D209/44
摘要:
A compound selected from those of formula (I): wherein m and n, which may be identical or different, each represent an integer from 0 to 2 inclusive, with the sum of the two integers being from 2 to 3 inclusive, p and q, which may be identical or different, each represent an integer from 0 to 2 inclusive, Alk represents an alkylene, alkenylene or alkynylene chain, X represents an oxygen atom, a sulphur atom or an —N(R)— group wherein R represents a hydrogen atom or an alkyl group, Y, Y′ and W are as defined in the description, its enantiomers, diastereoisomers, and addition salts thereof with one or more pharmaceutically acceptable acid or base. Medicinal products containing the same which are useful for treating conditions associated with central histaminergic systems.
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