发明授权
- 专利标题: Sleeve reaction chamber system
- 专利标题(中): 套筒反应室系统
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申请号: US09568618申请日: 2000-05-10
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公开(公告)号: US07578976B1公开(公告)日: 2009-08-25
- 发明人: M. Allen Northrup , Barton V. Beeman , William J. Benett , Dean R. Hadley , Phoebe Landre , Stacy L. Lehew , Peter A. Krulevitch
- 申请人: M. Allen Northrup , Barton V. Beeman , William J. Benett , Dean R. Hadley , Phoebe Landre , Stacy L. Lehew , Peter A. Krulevitch
- 申请人地址: US CA Livermore
- 专利权人: Lawrence Livermore National Security, LLC
- 当前专利权人: Lawrence Livermore National Security, LLC
- 当前专利权人地址: US CA Livermore
- 代理商 James S. Tak; Alan H. Thompson; John H. Lee
- 主分类号: G01N33/00
- IPC分类号: G01N33/00
摘要:
A chemical reaction chamber system that combines devices such as doped polysilicon for heating, bulk silicon for convective cooling, and thermoelectric (TE) coolers to augment the heating and cooling rates of the reaction chamber or chambers. In addition the system includes non-silicon-based reaction chambers such as any high thermal conductivity material used in combination with a thermoelectric cooling mechanism (i.e., Peltier device). The heat contained in the thermally conductive part of the system can be used/reused to heat the device, thereby conserving energy and expediting the heating/cooling rates. The system combines a micromachined silicon reaction chamber, for example, with an additional module/device for augmented heating/cooling using the Peltier effect. This additional module is particularly useful in extreme environments (very hot or extremely cold) where augmented heating/cooling would be useful to speed up the thermal cycling rates. The chemical reaction chamber system has various applications for synthesis or processing of organic, inorganic, or biochemical reactions, including the polymerase chain reaction (PCR) and/or other DNA reactions, such as the ligase chain reaction.