发明授权
US07585627B2 Polymorphism in tryptophan hydroxylase-2 controls brain serotonin synthesis
有权
色氨酸羟化酶-2的多态性控制脑血清素的合成
- 专利标题: Polymorphism in tryptophan hydroxylase-2 controls brain serotonin synthesis
- 专利标题(中): 色氨酸羟化酶-2的多态性控制脑血清素的合成
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申请号: US11133949申请日: 2005-05-20
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公开(公告)号: US07585627B2公开(公告)日: 2009-09-08
- 发明人: Marc G. Caron , Xiaodong Zhang , Martin Beaulieu , Raul R. Gainetdinov , Tatiana D. Sotnikova , Ranga R. Krishnan , David A. Schwartz , Lauranell Burch , Redford B. Williams
- 申请人: Marc G. Caron , Xiaodong Zhang , Martin Beaulieu , Raul R. Gainetdinov , Tatiana D. Sotnikova , Ranga R. Krishnan , David A. Schwartz , Lauranell Burch , Redford B. Williams
- 申请人地址: US NC Durham
- 专利权人: Duke University
- 当前专利权人: Duke University
- 当前专利权人地址: US NC Durham
- 代理机构: Myers Bigel Sibley & Sajovec, P.A.
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; G01N33/567 ; C12P19/34
摘要:
A method of screening a subject for a serotonergic neurotransmission dysregulation disorder comprises detecting the presence or absence of an Tph2 mutation in the subject; and then determining that the subject is at increased risk of a serotonergic neurotransmission dysregulation disorder due to the presence or absence of the Tph2 mutation.
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