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US07585851B2 3′-prodrugs of 2′-deoxy-β-L-nucleosides 有权
2'-脱氧-β-L-核苷的3'-前药

3′-prodrugs of 2′-deoxy-β-L-nucleosides
摘要:
The present invention relates to compounds, compositions and methods for the treatment of a host infected with a hepatitis B virus. Specifically, compound and compositions of 3′-esters of 2′-deoxy-β-L-pyrimidine nucleosides are disclosed, which can be administered either alone or in combination with other anti-hepatitis B agents. Compound and compositions of 3′,5′-diesters of 2′-deoxy-β-L-pyrimidine nucleosides are also disclosed, which can be administered either alone or in combination with other anti-hepatitis B agents.
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