Invention Grant
US07589105B2 Preventives or remedies for alzheimer's disease, or amyloid protein fibril-formation inhibitors, which include a nitrogen-containing heteroaryl compound
失效
阿尔茨海默病或淀粉样蛋白原纤维形成抑制剂的预防或补救措施，其包括含氮杂芳基化合物
- Patent Title: Preventives or remedies for alzheimer's disease, or amyloid protein fibril-formation inhibitors, which include a nitrogen-containing heteroaryl compound
- Patent Title (中): 阿尔茨海默病或淀粉样蛋白原纤维形成抑制剂的预防或补救措施，其包括含氮杂芳基化合物
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Application No.: US10497183Application Date: 2002-11-25
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Publication No.: US07589105B2Publication Date: 2009-09-15
- Inventor: Masaki Meguro , Tomiichiro Oda , Yasuhiro Nakagami , Shinji Marumoto , Kazuo Koyama , Isao Kaneko
- Applicant: Masaki Meguro , Tomiichiro Oda , Yasuhiro Nakagami , Shinji Marumoto , Kazuo Koyama , Isao Kaneko
- Applicant Address: GB London
- Assignee: BTG International Limited
- Current Assignee: BTG International Limited
- Current Assignee Address: GB London
- Agency: Nixon & Vanderhye
- Priority: JP2001-361847 20011128; JP2002-192777 20020702
- International Application: PCT/JP02/12265 WO 20021125
- International Announcement: WO03/045923 WO 20030605
- Main IPC: A01N43/60
- IPC: A01N43/60 ; A01N43/42
Abstract:
Pharmaceutical compositions and methods of treatment are provided for treating amyloidosis, containing, as an active ingredient, at least one nitrogen-containing heteroaryl compound represented by the following general formula or a pharmacologically permitted salt thereof; together with nitrogen-containing heteroaryl derivatives, and pharmacologically permitted salts thereof: where, R1, R2, Z1-Z5, and A are as defined herein.
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