发明授权
- 专利标题： Mitotic kinesin inhibitors
- 专利标题（中）： 有丝分裂驱动蛋白抑制剂
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申请号： US11883507申请日： 2006-02-06
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公开(公告)号： US07595337B2公开(公告)日： 2009-09-29
- 发明人: Michael J. Breslin , Paul J. Coleman , Christopher D. Cox , Lou Anne Neilson , David B. Whitman
- 申请人： Michael J. Breslin , Paul J. Coleman , Christopher D. Cox , Lou Anne Neilson , David B. Whitman
- 申请人地址： US NJ Rahway
- 专利权人： Merck & Co. Inc.
- 当前专利权人： Merck & Co. Inc.
- 当前专利权人地址： US NJ Rahway
- 代理商 Nicole M. Beeler; David A. Muthard
- 国际申请： PCT/US2006/004214 WO 20060206
- 国际公布： WO2006/086358 WO 20060817
- 主分类号： A61K31/4162
- IPC分类号： A61K31/4162 ; C07D231/54
摘要：
The present invention relates to tricyclic pyrazoles that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also relates to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
公开/授权文献
- US20080182843A1 Mitotic Kinesin Inhibitors 公开/授权日：2008-07-31
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