发明授权
- 专利标题: Imidazo[4,5-b]pyrazinone inhibitors of protein kinases
- 专利标题(中): 咪唑并[4,5-b]吡嗪酮抑制蛋白激酶
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申请号: US11233725申请日: 2005-09-23
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公开(公告)号: US07608622B2公开(公告)日: 2009-10-27
- 发明人: Jian Liu , Raymond J. Patch , Mark R. Player , Huaping Hu
- 申请人: Jian Liu , Raymond J. Patch , Mark R. Player , Huaping Hu
- 申请人地址: BE
- 专利权人: Janssen Pharmaceutica NV
- 当前专利权人: Janssen Pharmaceutica NV
- 当前专利权人地址: BE
- 主分类号: A01N43/58
- IPC分类号: A01N43/58 ; A61K31/50 ; A01N43/60 ; A61K31/495 ; C07D471/00 ; C07D487/00 ; C07D491/00 ; C07D495/00 ; C07D497/00
摘要:
The invention is directed to compounds of Formula I: wherein Q, Y, A are set forth in the specification, as well as solvates, hydrates, tautomers or pharmaceutically acceptable salts thereof, that inhibit protein kinases, especially Aurora-1, Aurora-2 and Aurora-3 kinases.
公开/授权文献
- US20060106022A1 Imidazo[4,5-b]pyrazinone inhibitors of protein kinases 公开/授权日:2006-05-18