公开(公告)号：US07608622B2

公开(公告)日：2009-10-27

申请号：US11233725

申请日：2005-09-23

申请人： Jian Liu ,  Raymond J. Patch ,  Mark R. Player ,  Huaping Hu

发明人： Jian Liu ,  Raymond J. Patch ,  Mark R. Player ,  Huaping Hu

IPC分类号： A01N43/58 ,  A61K31/50 ,  A01N43/60 ,  A61K31/495 ,  C07D471/00 ,  C07D487/00 ,  C07D491/00 ,  C07D495/00 ,  C07D497/00

CPC分类号： C07D487/04

摘要： The invention is directed to compounds of Formula I: wherein Q, Y, A are set forth in the specification, as well as solvates, hydrates, tautomers or pharmaceutically acceptable salts thereof, that inhibit protein kinases, especially Aurora-1, Aurora-2 and Aurora-3 kinases.

摘要翻译： 本发明涉及式I化合物：其中Q，Y，A在本说明书中列出，以及其抑制蛋白激酶，特别是Aurora-1，Aurora-2的溶剂合物，水合物，互变异构体或其药学上可接受的盐 和Aurora-3激酶。

公开(公告)号：US20110190364A1

公开(公告)日：2011-08-04

申请号：US13084718

申请日：2011-04-12

申请人： Mark R. Player ,  Scott L. Dax ,  William H. Parsons ,  Michael Richard Brandt ,  Raul R. Calvo ,  Sharmila Patel ,  Jian Liu ,  Wing S. Cheung ,  Michele C. Jetter ,  Yu-Kai Lee ,  Mark A. Youngman ,  Wenxi Pan ,  Kenneth M. Wells ,  Derek A. Beauchamp

发明人： Mark R. Player ,  Scott L. Dax ,  William H. Parsons ,  Michael Richard Brandt ,  Raul R. Calvo ,  Sharmila Patel ,  Jian Liu ,  Wing S. Cheung ,  Michele C. Jetter ,  Yu-Kai Lee ,  Mark A. Youngman ,  Wenxi Pan ,  Kenneth M. Wells ,  Derek A. Beauchamp

IPC分类号： A61K31/4184 ,  A61P29/00

CPC分类号： C07D401/06 ,  C07D235/08 ,  C07D403/06

摘要： The invention is directed to compounds of Formula (I): to pharmaceutical compositions containing such compounds and to methods of treatment using them.

摘要翻译： 本发明涉及式（I）的化合物：含有这些化合物的药物组合物和使用它们的治疗方法。

公开(公告)号：US20070259936A1

公开(公告)日：2007-11-08

申请号：US11734984

申请日：2007-04-13

申请人： Mark R. Player ,  Scott L. Dax ,  William H. Parsons ,  Michael Richard Brandt ,  Raul R. Calvo ,  Sharmila Patel ,  Jian Liu ,  Wing S. Cheung ,  Michele C. Jetter ,  Yu-Kai Lee ,  Mark A. Youngman ,  Wenxi Pan ,  Kenneth M. Weils ,  Derek A. Beauchamp

发明人： Mark R. Player ,  Scott L. Dax ,  William H. Parsons ,  Michael Richard Brandt ,  Raul R. Calvo ,  Sharmila Patel ,  Jian Liu ,  Wing S. Cheung ,  Michele C. Jetter ,  Yu-Kai Lee ,  Mark A. Youngman ,  Wenxi Pan ,  Kenneth M. Weils ,  Derek A. Beauchamp

IPC分类号： A61K31/4184

CPC分类号： C07D401/06 ,  C07D235/08 ,  C07D403/06

摘要： The invention is directed to compounds of Formula (I): to pharmaceutical compositions containing such compounds and to methods of treatment using them.

摘要翻译： 本发明涉及式（I）的化合物：含有这些化合物的药物组合物和使用它们的治疗方法。

公开(公告)号：US20110190344A1

公开(公告)日：2011-08-04

申请号：US13084705

申请日：2011-04-12

申请人： Mark R. Player ,  Scott L. Dax ,  William H. Parsons ,  Michael Richard Brandt ,  Raul R. Calvo ,  Sharmila Patel ,  Jian Liu ,  Wing S. Cheung ,  Michele C. Jetter ,  Yu-Kai Lee ,  Mark A. Youngman ,  Wenxi Pan ,  Kenneth M. Wells ,  Derek A. Beauchamp

发明人： Mark R. Player ,  Scott L. Dax ,  William H. Parsons ,  Michael Richard Brandt ,  Raul R. Calvo ,  Sharmila Patel ,  Jian Liu ,  Wing S. Cheung ,  Michele C. Jetter ,  Yu-Kai Lee ,  Mark A. Youngman ,  Wenxi Pan ,  Kenneth M. Wells ,  Derek A. Beauchamp

IPC分类号： A61K31/4184 ,  C07D235/04 ,  C07D401/10 ,  A61K31/4709 ,  A61P25/00

CPC分类号： C07D401/06 ,  C07D235/08 ,  C07D403/06

摘要： The invention is directed to compounds of Formula (I): to pharmaceutical compositions containing such compounds and to methods of treatment using them.

公开(公告)号：US07951829B2

公开(公告)日：2011-05-31

申请号：US11734984

申请日：2007-04-13

申请人： Mark R. Player ,  Scott L. Dax ,  William H. Parsons ,  Michael Richard Brandt ,  Raul R. Calvo ,  Sharmila Patel ,  Jian Liu ,  Wing S. Cheung ,  Michele C. Jetter ,  Yu-Kai Lee ,  Mark A. Youngman ,  Wenxi Pan ,  Kenneth M. Wells ,  Derek A. Beauchamp

发明人： Mark R. Player ,  Scott L. Dax ,  William H. Parsons ,  Michael Richard Brandt ,  Raul R. Calvo ,  Sharmila Patel ,  Jian Liu ,  Wing S. Cheung ,  Michele C. Jetter ,  Yu-Kai Lee ,  Mark A. Youngman ,  Wenxi Pan ,  Kenneth M. Wells ,  Derek A. Beauchamp

IPC分类号： A01N43/52 ,  C07D235/00

CPC分类号： C07D401/06 ,  C07D235/08 ,  C07D403/06

摘要： The invention is directed to compounds of Formula (I): to pharmaceutical compositions containing such compounds and to methods of treatment using them.

摘要翻译： 本发明涉及式（I）的化合物：含有这些化合物的药物组合物和使用它们的治疗方法。

公开(公告)号：US20100113473A1

公开(公告)日：2010-05-06

申请号：US12582325

申请日：2009-10-20

申请人： Mark R. Player ,  Jian Liu

发明人： Mark R. Player ,  Jian Liu

IPC分类号： A61K31/496 ,  C07D401/14 ,  A61P9/00 ,  A61P3/10 ,  A61P3/04 ,  A61P3/06 ,  A61P31/00 ,  A61P29/00 ,  A61P35/00

CPC分类号： C07D405/14

摘要： An aryl amide compound of Formula (I): or a pharmaceutically acceptable form thereof is disclosed. The compound is an ACC inhibitor and therefore useful in treating an ACC-mediated condition.

摘要翻译： 公开了式（I）的芳基酰胺化合物或其药学上可接受的形式。 该化合物是ACC抑制剂，因此可用于治疗ACC介导的病症。

公开(公告)号：US07326788B2

公开(公告)日：2008-02-05

申请号：US10894940

申请日：2004-07-20

申请人： Mark J. Wall ,  Mark R. Player ,  Raymond Joseph Patch ,  Sanath Meegalla ,  Jian Liu ,  Carl R. Illig ,  Wing Cheung ,  Jinsheng Chen ,  Davoud Asgari

发明人： Mark J. Wall ,  Mark R. Player ,  Raymond Joseph Patch ,  Sanath Meegalla ,  Jian Liu ,  Carl R. Illig ,  Wing Cheung ,  Jinsheng Chen ,  Davoud Asgari

IPC分类号： C07D215/38 ,  C07D215/44

CPC分类号： C07D215/227 ,  C07D401/04 ,  C07D409/04 ,  C07D413/04 ,  C07D413/14 ,  C07D417/04 ,  C07D471/04 ,  Y02P20/582

摘要： The invention is directed to compounds of Formulae I and II: wherein R1, R2, R3, R5, R6, Y1, Y2, Y3, Y4 and X are set forth in the specification, as well as solvates, hydrates, tautomers or pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially c-fms kinase.

摘要翻译： 本发明涉及式I和II的化合物：其中R 1，R 2，R 3，R 5， 其中，R 6，R 6，Y 1，Y 2，Y 3，Y 4， SUP＆amp; X和X在本说明书中列出，以及其抑制蛋白酪氨酸激酶，特别是c-fms激酶的溶剂合物，水合物，互变异构体或其药学上可接受的盐。

公开(公告)号：USD1019826S1

公开(公告)日：2024-03-26

申请号：US29916182

申请日：2023-11-08

申请人： Jian Liu

设计人： Jian Liu

摘要： FIG. 1 is a front, top perspective view of a glider exercise device, showing my new design;
FIG. 2 is a rear, bottom perspective view thereof;
FIG. 3 is a front elevation view thereof;
FIG. 4 is a rear elevation view thereof;
FIG. 5 is a left side elevation view thereof;
FIG. 6 is a right side elevation view thereof;
FIG. 7 is a top plan view thereof; and,
FIG. 8 is a bottom plan view thereof.

公开(公告)号：US20230046316A1

公开(公告)日：2023-02-16

申请号：US17885130

申请日：2022-08-10

申请人： Jian Liu ,  Lakshmi Ravi ,  Dong Dong ,  Rolando Burgos ,  Steven Schmalz

发明人： Jian Liu ,  Lakshmi Ravi ,  Dong Dong ,  Rolando Burgos ,  Steven Schmalz

IPC分类号： H01H9/54 ,  H01H33/59

摘要： Gate control of power semiconductor devices using reduced gate drivers is disclosed. A circuit breaker may include a multitude of transistors, such as insulated gate bipolar transistors (IGBTs), connected in series with one another. Each transistor may be connected to a respective gate resistor. Diodes may be connected between various gate resistors. One or more resistor-capacitor (RC) snubber circuits may be provided in parallel with one or more of the transistors. Likewise, one or more metal-oxide varistors (MOVs) may be connected in parallel to one or more of the transistors. A gate driver (e.g., a single gate drive) may be connected to the one or more diodes and an emitter of at least one of transistors.

公开(公告)号：US11465240B2

公开(公告)日：2022-10-11

申请号：US16378485

申请日：2019-04-08

申请人： Jian Liu

发明人： Jian Liu

IPC分类号： B23K26/34 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y50/02 ,  G01N21/19 ,  G01N21/71 ,  G01N21/88 ,  G01N21/17 ,  G01B11/30 ,  B22F10/20 ,  B22F10/36 ,  B22F10/28 ,  B22F10/30 ,  B22F10/50 ,  B22F12/90 ,  B29C64/393 ,  B23K26/354 ,  G01J5/00 ,  G01J5/80

摘要： Methods and apparatuses for manufacturing are disclosed, including (a) providing an apparatus having: a laser; scanner; powder injection system; powder spreading system; dichroic filter; imager-and-processor; and computer; (b) programming the computer with specifications of a sample; (c) using the computer to set initial parameters based on the sample specifications; (d) adjusting a stage to position the sample; (e) focusing and scanning electromagnetic radiation onto the sample while powder is concurrently injected onto the sample in order to deposit a layer; (f) capturing two-dimensional images of the sample and probing the sample to determine whether the deposited layer was manufactured per the specifications; (g) use the computer to adjust the three-dimensional manufacturing parameters based on the determination made in step (f) prior to additively manufacturing a subsequent layer or making repairs; and (h) repeating steps (d), (e), (f), and (g) until the manufacture is complete. Other embodiments are described and claimed.