发明授权
- 专利标题: Bifunctional-modified hydrogels
- 专利标题(中): 双功能改性水凝胶
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申请号: US10128198申请日: 2002-04-23
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公开(公告)号: US07615593B2公开(公告)日: 2009-11-10
- 发明人: Weiyun John Kao , Jing Li , David Lok , Rathna Gundloori
- 申请人: Weiyun John Kao , Jing Li , David Lok , Rathna Gundloori
- 申请人地址: US WI Madison
- 专利权人: Wisconsin Alumni Research Foundation
- 当前专利权人: Wisconsin Alumni Research Foundation
- 当前专利权人地址: US WI Madison
- 代理机构: Michael Best & Friedrich LLP
- 主分类号: A61K47/30
- IPC分类号: A61K47/30 ; A61G47/48 ; C08F63/91 ; A61L2/00 ; A61N24/00 ; C12N11/02
摘要:
Disclosed are hydrogels wherein a polymer matrix is modified to contain a bifunctional poly(alkylene glycol) molecule covalently bonded to the polymer matrix. The hydrogels can be cross-linked using, for example, glutaraldehyde. The hydrogels may also be crosslinked via an interpenetrating network of a photopolymerizable acrylates. The hydrogels may also be modified to have pharmacologically-active agents covalently bonded to the poly(alkylene glycol) molecules or entrained within the hydrogel. Living cells may also be entrained within the hydrogels.
公开/授权文献
- US20030083389A1 Bifunctional-modified hydrogels 公开/授权日:2003-05-01
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