- 专利标题： Mitotic kinesin inhibitors
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申请号： US11630224申请日： 2005-06-27
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公开(公告)号： US07618971B2公开(公告)日： 2009-11-17
- 发明人: Paul J. Coleman , Christopher D. Cox , Mark E. Fraley , George D. Hartman , John Schreier
- 申请人： Paul J. Coleman , Christopher D. Cox , Mark E. Fraley , George D. Hartman , John Schreier
- 申请人地址： US NJ Rahway
- 专利权人： Merck & Co. Inc.
- 当前专利权人： Merck & Co. Inc.
- 当前专利权人地址： US NJ Rahway
- 代理商 Nicole M. Beeler; David A. Muthard
- 国际申请： PCT/US2005/022877 WO 20050627
- 国际公布： WO2006/007496 WO 20060119
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; A61K31/4196 ; A61K31/4155 ; C07D403/06 ; C07D249/08 ; C07D231/06
摘要：
The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
公开/授权文献
- US20080027058A1 Mitotic Kinesin Inhibitors 公开/授权日：2008-01-31
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