发明授权
US07622118B2 Cancer treatment methods using selected antibodies to aminophospholipids
有权
使用氨基磷脂选择的抗体的癌症治疗方法
- 专利标题： Cancer treatment methods using selected antibodies to aminophospholipids
- 专利标题（中）： 使用氨基磷脂选择的抗体的癌症治疗方法
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申请号： US10642071申请日： 2003-08-15
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公开(公告)号： US07622118B2公开(公告)日： 2009-11-24
- 发明人: Philip E. Thorpe , Sophia Ran
- 申请人： Philip E. Thorpe , Sophia Ran
- 申请人地址： US TX Austin
- 专利权人： Board of Regents, The University of Texas System
- 当前专利权人： Board of Regents, The University of Texas System
- 当前专利权人地址： US TX Austin
- 代理商 Shelley P. M. Fussey
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61K39/00
摘要：
Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases.
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